Advanced image-based virtual monoenergetic dual-energy CT angiography of the abdomen: optimization of kiloelectron volt settings to improve image contrast

Eur Radiol. 2016 Jun;26(6):1863-70. doi: 10.1007/s00330-015-3970-2. Epub 2015 Sep 3.

Abstract

Objectives: To compare quantitative image quality parameters in abdominal dual-energy computed tomography angiography (DE-CTA) using an advanced image-based (Mono+) reconstruction algorithm for virtual monoenergetic imaging and standard DE-CTA.

Methods: Fifty-five patients (36 men; mean age, 64.2 ± 12.7 years) who underwent abdominal DE-CTA were retrospectively included. Mono + images were reconstructed at 40, 50, 60, 70, 80, 90 and 100 keV levels and as standard linearly blended M_0.6 images (60 % 100 kV, 40 % 140 kV). The contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) of the common hepatic (CHA), splenic (SA), superior mesenteric (SMA) and left renal arteries (LRA) were objectively measured.

Results: Mono+ DE-CTA series showed a statistically superior CNR for 40, 50, 60, 70 and 80 keV (P < 0.031) compared to M_0.6 images for all investigated arteries except SMA at 80 keV (P = 0.08). CNR at 40 keV revealed a mean relative increase of 287.7 % compared to linearly blended images among all assessed arteries (P < 0.001). SNR of Mono+ images was consistently significantly higher at 40, 50, 60 and 70 keV compared to M_0.6 for CHA and SA (P < 0.009).

Conclusions: Compared to linearly blended images, Mono+ reconstructions at low keV levels of abdominal DE-CTA datasets significantly improve quantitative image quality.

Key points: • Mono+ combines increased attenuation with reduced image noise compared to standard DE-CTA. • Mono+ shows superior contrast-to-noise ratios at low keV compared to linearly-blended images. • Contrast-to-noise ratio in monoenergetic DE-CTA peaks at 40 keV. • Mono+ reconstructions significantly improve quantitative image quality at low keV levels.

Keywords: Computed tomography angiography; Dual-energy CT; Image quality; Monochromatic imaging; Monoenergetic plus.

MeSH terms

  • Abdominal Cavity / diagnostic imaging*
  • Algorithms*
  • Computed Tomography Angiography / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Radiography, Dual-Energy Scanned Projection / methods*
  • Retrospective Studies
  • Signal-To-Noise Ratio