Maintaining What Is Already There: Strategies to Rectify HSC Transplantation Dilemmas

Claudia Waskow

doi:10.1016/j.stem.2015.08.012

Maintaining What Is Already There: Strategies to Rectify HSC Transplantation Dilemmas

Cell Stem Cell. 2015 Sep 3;17(3):258-9. doi: 10.1016/j.stem.2015.08.012.

Author

Claudia Waskow¹

Affiliation

¹ Regeneration in Hematopoiesis and Animal Models in Hematopoiesis, Institute for Immunology, Faculty of Medicine, TU Dresden, Fetscherstrasse 74, 01307 Dresden, Germany. Electronic address: [email protected].

PMID: 26340525
DOI: 10.1016/j.stem.2015.08.012

Abstract

Hematopoietic stem cell (HSC) transplantation remains the only cure for various hematological diseases, but low HSC numbers in many donor samples are a critical problem preventing their clinical use. Now in Nature and Cell, two creative strategies to rescue and improve pre-existing engraftment potential are presented.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

8,11,14-Eicosatrienoic Acid / analogs & derivatives*
Animals
Bone Marrow*
Female
Fetal Blood / cytology*
Hematopoiesis*
Hematopoietic Stem Cell Transplantation*
Hematopoietic Stem Cells / cytology*
Humans
Male
Zebrafish / embryology*

Substances

8,11,14-Eicosatrienoic Acid