Strategies and long-term outcomes in the surgical management of tympanojugular paragangliomas

Head Neck. 2016 Jun;38(6):871-85. doi: 10.1002/hed.24177. Epub 2015 Sep 7.

Abstract

Background: The purpose of this study was to share our review of surgical strategies and long-term outcomes in the management of tympanojugular paragangliomas.

Methods: This was a retrospective study with a literature review. The records of 184 patients with 185 tympanojugular paragangliomas were analyzed for tumor class, surgical procedure, preoperative vascular management, and perioperative sequelae.

Results: Of class C1, C2, C3, and C4 tumors, we found 46 (24.9%), 95 (51.3%), 41 (22.2%), and 3 (1.6%), respectively. One hundred four (56.2%) tumors had intracranial extensions and 8 (4.3%) involved the vertebral artery. A single-stage procedure was adopted in 158 (85.4%) tumors. The infratemporal fossa type A approach was used in all cases. In 17 patients (9.7%), an intra-arterial stenting of the internal carotid artery was performed. Gross-total tumor removal was achieved in 166 cases (89.7%) and 4 (2.4%) among them developed a recurrence.

Conclusion: A thorough understanding of skull base techniques and a logical decision-making process in the management of tympanojugular paragangliomas can achieve a high rate of success in terms of recurrences and complications. © 2015 Wiley Periodicals, Inc. Head Neck 38: 871-885, 2016.

Keywords: facial nerve; infratemporal fossa approach; lower cranial nerves; radiotherapy (RT); tympanojugular paragangliomas; wait-and-scan.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cranial Nerves / pathology
  • Female
  • Glomus Jugulare Tumor / diagnostic imaging
  • Glomus Jugulare Tumor / pathology
  • Glomus Jugulare Tumor / radiotherapy
  • Glomus Jugulare Tumor / surgery*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local
  • Radiotherapy, Adjuvant
  • Retrospective Studies
  • Skull Base Neoplasms / diagnostic imaging
  • Skull Base Neoplasms / pathology
  • Skull Base Neoplasms / radiotherapy
  • Skull Base Neoplasms / surgery*
  • Surgical Procedures, Operative / methods
  • Temporal Bone / surgery*
  • Treatment Outcome