The detection and genetic characterization based on the S1 gene region of BCoVs from respiratory and enteric infections in Turkey

Transbound Emerg Dis. 2011 Apr;58(2):179-85. doi: 10.1111/j.1865-1682.2010.01194.x. Epub 2011 Jan 5.

Abstract

We investigated bovine coronavirus (BCoV) as an etiological agent in cattle with clinical respiratory and digestive signs using 147 feces and 199 nasal swab samples. A total of 18 test samples (16 feces and 2 nasal swap samples) were detected positive by ELISA and/or RT-PCR targeting the BCoV N gene. The partial S1 gene regions of BCoVs (An-4 and An-11) detected in feces samples from two herd-mate dairy calves were compared. Virological and serological results indicated that BCoVs are widespread in Turkey and are likely etiological agents in diarrhea cases in calves.

Keywords: S1 gene region; bovine; coronavirus; nested RT-PCR; sequencing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases / epidemiology*
  • Cattle Diseases / virology
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / veterinary*
  • Coronavirus Infections / virology
  • Coronavirus, Bovine / genetics*
  • Coronavirus, Bovine / isolation & purification
  • Coronavirus, Bovine / metabolism
  • Enzyme-Linked Immunosorbent Assay / veterinary
  • Feces / virology
  • Molecular Sequence Data
  • Nose / virology
  • Phylogeny
  • Sequence Analysis, DNA / veterinary
  • Spike Glycoprotein, Coronavirus / genetics*
  • Spike Glycoprotein, Coronavirus / metabolism
  • Turkey / epidemiology

Substances

  • Spike Glycoprotein, Coronavirus

Associated data

  • GENBANK/GQ259978
  • GENBANK/GQ259979