GVHD and miR: good things in small packages

Blood. 2015 Sep 10;126(11):1265-7. doi: 10.1182/blood-2015-07-657114.

Abstract

In this issue of Blood, Wu et al demonstrate that a cluster of microRNAs (miRs) previously shown to be important in malignant disease and B-cell development plays a critical role in the proinflammatory function of donor T cells that mediate acute graft-versus-host disease (GVHD).

Publication types

  • Comment

MeSH terms

  • Animals
  • Graft vs Host Disease / immunology*
  • Leukemia, Experimental / immunology*
  • MicroRNAs / genetics*
  • MicroRNAs / immunology*
  • T-Lymphocytes / immunology*

Substances

  • MicroRNAs