5,5'-Diamino-BIPHEP ligands bearing small selector units for non-covalent binding of chiral analytes in solution

G Storch; M Siebert; F Rominger; O Trapp

doi:10.1039/c5cc06306j

5,5'-Diamino-BIPHEP ligands bearing small selector units for non-covalent binding of chiral analytes in solution

Chem Commun (Camb). 2015 Nov 7;51(86):15665-8. doi: 10.1039/c5cc06306j.

Authors

G Storch¹, M Siebert, F Rominger, O Trapp

Affiliation

¹ Organisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany. [email protected].

PMID: 26361251
DOI: 10.1039/c5cc06306j

Abstract

A dynamic axially chiral BIPHEP-ligand with 3,5-dichlorobenzoyl amide selector units for non-covalent binding of phenylalanine derivatives has been developed. Interaction studies in solution were performed with rhodium(i) complexes under exclusion of the metal being involved in binding. (Rax, S(Phe)) and (Sax, S(Phe)) adducts were observed as significantly separated species in NMR spectroscopy.