Hemorrhagic fever with renal syndrome-related encephalopathy: magnetic resonance imaging findings

Clin Imaging. 2015 Nov-Dec;39(6):975-8. doi: 10.1016/j.clinimag.2015.08.007. Epub 2015 Aug 15.

Abstract

Objective: To report the incidence and findings of brain magnetic resonance imaging (MRI) in patients with hemorrhagic fever with renal syndrome (HFRS)-related encephalopathy along with its clinical course.

Methods: Medical records and brain MRI were reviewed from January 2004 to January 2013. The final cohort consisted of 145 patients. Brain MRI findings were correlated with associated clinical stage of disease.

Results: The MRI findings associated with clinical course of HFRS-related encephalopathy were posterior reversible encephalopathy syndrome pattern (n=3) in oliguric phase and splenial lesion pattern (n=1) in febrile phase.

Conclusions: Brain MRI findings in HFRS-related encephalopathy may be associated with the clinical course of HFRS.

Keywords: Diffusion-weighted imaging; Encephalopathy; Hemorrhagic fever with renal syndrome; Magnetic resonance imaging.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brain / pathology*
  • Disease Progression
  • Female
  • Hemorrhagic Fever with Renal Syndrome / complications
  • Hemorrhagic Fever with Renal Syndrome / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neuroimaging
  • Posterior Leukoencephalopathy Syndrome / complications
  • Posterior Leukoencephalopathy Syndrome / pathology*
  • Retrospective Studies
  • Young Adult