[Acute anterior myocardial infarction as presenting feature of antiphospholipid syndrome related lupus arthritis]

Rev Med Interne. 2016 May;37(5):371-4. doi: 10.1016/j.revmed.2015.08.010. Epub 2015 Sep 9.
[Article in French]

Abstract

Introduction: Antiphospholipid syndrome is an autoimmune disorder causing venous and arterial thrombosis. Acute coronary complications are rare but potentially dramatic.

Case report: We report a 39-year-old woman who presented with an acute anterior myocardial infarction after intravenous corticosteroids as part of the treatment of lupus arthritis and revealing antiphospholipid syndrome. Emergency coronary angiography was performed with drug-eluting stent angioplasty despite the need for anticoagulation and dual antiplatelet therapy.

Conclusion: Antiplatelet and anticoagulant therapy management is pivotal in patients with antiphospholipid syndrome and acute coronary syndrome to prevent thrombosis recurrence.

Keywords: Acute coronary syndrome; Angioplastie coronaire percutanée; Antiagrégation plaquettaire; Anticoagulation; Antiphospholipid antibody syndrome; Antiplatelet therapy; Percutaneous coronary intervention; Syndrome coronaire aigu; Syndrome des antiphospholipides.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticoagulants / therapeutic use
  • Antiphospholipid Syndrome / diagnosis*
  • Antiphospholipid Syndrome / etiology*
  • Arthritis / diagnosis
  • Arthritis / drug therapy
  • Arthritis / etiology*
  • Coronary Angiography
  • Diagnosis, Differential
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / diagnosis
  • Lupus Erythematosus, Systemic / drug therapy
  • Myocardial Infarction / diagnosis
  • Myocardial Infarction / etiology*
  • Percutaneous Coronary Intervention

Substances

  • Anticoagulants