Mitochondrial transport of protoporphyrinogen IX in erythroid cells

Oncotarget. 2015 Aug 28;6(25):20742-3. doi: 10.18632/oncotarget.5124.

Authors

Yvette Y Yien¹, Alessa R Ringel^{1

2}, Barry H Paw^{1

3

4}

Affiliations

¹ Hematology Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
² Institut für Biologie und Biotechnologie der Pflanzen, Westfälische Wilhelms-Universität Münster, Münster, Germany.
³ Hematology-Oncology Division, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
⁴ Pediatric Oncology Department, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

Abstract

Comment on: Yien Y, et al. TMEM14C is required for erythroid mitochondrial heme metabolism. J. Clin. Invest. 2014; 124:4294-4304.

Keywords: Tmem14c; heme synthesis; porphyrin transporters.

Publication types

Editorial

MeSH terms

Animals
Biological Transport
Erythroid Cells / metabolism*
Heme / chemistry
Homeostasis
Humans
Mice
Mitochondria / metabolism*
Protoporphyrins / physiology*
Sequence Analysis, RNA
Zebrafish

Substances

Protoporphyrins
Heme
protoporphyrinogen

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