Interrelationships between indices of longitudinal movement of the common carotid artery wall and the conventional measures of subclinical arteriosclerosis

Clin Physiol Funct Imaging. 2017 May;37(3):305-313. doi: 10.1111/cpf.12305. Epub 2015 Sep 16.

Abstract

Our objective was to study the interrelationships between longitudinal movement of the wall of the common carotid artery and the conventional measures of arteriosclerosis in a large and well-characterized study population. Successful longitudinal movement analyses were performed on 292 subjects. The peak-to-peak and retrograde amplitudes of the longitudinal movement were directly correlated with carotid artery distensibility (r = 0·21, P<0·001 and r = 0·23, P<0·001, respectively) and inversely correlated with pulse wave velocity (r = -0·14, P<0·05 and r = -0·17, P<0·01, respectively). All longitudinal motion parameters were independent of brachial flow-mediated dilatation and intima-media thickness. Our findings indicate that arterial stiffening modulates longitudinal movement and, therefore, measurement of longitudinal movement can be of value in the assessment of vascular health.

Keywords: arterial stiffness; carotid artery distensibility; flow-mediated dilatation; intima-media thickness; motion tracking; pulse wave velocity; ultrasound imaging.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Asymptomatic Diseases
  • Biomechanical Phenomena
  • Blood Flow Velocity
  • Brachial Artery / diagnostic imaging
  • Brachial Artery / physiopathology
  • Carotid Artery Diseases / diagnostic imaging*
  • Carotid Artery Diseases / physiopathology
  • Carotid Artery, Common / diagnostic imaging*
  • Carotid Artery, Common / physiopathology
  • Carotid Intima-Media Thickness
  • Cross-Sectional Studies
  • Female
  • Finland
  • Humans
  • Male
  • Middle Aged
  • Models, Cardiovascular
  • Predictive Value of Tests
  • Pulse Wave Analysis
  • Regional Blood Flow
  • Ultrasonography / methods*
  • Vascular Stiffness*
  • Vasodilation
  • Video Recording