Comparison of Molecular Characteristics of Mycoplasma pneumoniae Specimens Collected from the United States and China

J Clin Microbiol. 2015 Dec;53(12):3891-3. doi: 10.1128/JCM.02468-15.

Abstract

Mycoplasma pneumoniae-positive clinical specimens obtained from the United States and China during the same period were studied for their molecular characteristics. We found much more diverse genotypes and a lower prevalence of macrolide resistance in the U.S. specimens. Data from the study also showed an association of the resistance with certain genotypes.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology
  • Child
  • Child, Preschool
  • China / epidemiology
  • Drug Resistance, Bacterial
  • Genetic Variation*
  • Genotype
  • Humans
  • Infant
  • Infant, Newborn
  • Macrolides / pharmacology
  • Mycoplasma pneumoniae / classification*
  • Mycoplasma pneumoniae / drug effects
  • Mycoplasma pneumoniae / genetics*
  • Mycoplasma pneumoniae / isolation & purification
  • Pneumonia, Mycoplasma / epidemiology
  • Pneumonia, Mycoplasma / microbiology*
  • Prevalence
  • United States / epidemiology

Substances

  • Anti-Bacterial Agents
  • Macrolides