Monitoring of chronic γ-secretase modulator treatment by serial amyloid-PET

Mol Psychiatry. 2015 Oct;20(10):1141. doi: 10.1038/mp.2015.146.
No abstract available

MeSH terms

  • Amyloid Precursor Protein Secretases / analysis*
  • Amyloid Precursor Protein Secretases / antagonists & inhibitors
  • Amyloid Precursor Protein Secretases / metabolism
  • Amyloid beta-Peptides / metabolism
  • Animals
  • Brain / diagnostic imaging*
  • Brain / enzymology*
  • Mice
  • Positron-Emission Tomography / methods*

Substances

  • Amyloid beta-Peptides
  • Amyloid Precursor Protein Secretases