NIR-Responsive On-Demand Release of CO from Metal Carbonyl-Caged Graphene Oxide Nanomedicine

Adv Mater. 2015 Nov;27(42):6741-6. doi: 10.1002/adma.201502762. Epub 2015 Sep 24.

Abstract

On-demand release of carbon monoxide (CO) is realized through a novel near-infrared-responsive nanomedicine in favor of the enhancement of therapy efficacy and biosafety of CO therapy.

Keywords: CO therapy; controlled release; drug delivery; graphene; nanomedicine.

Publication types

  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / radiation effects
  • Carbon Monoxide / administration & dosage*
  • Carbon Monoxide / chemistry
  • Carbon Monoxide / radiation effects*
  • Cell Line
  • Drug Delivery Systems / methods
  • Electrons
  • Graphite / chemistry*
  • Light*
  • Mice
  • Microscopy, Atomic Force
  • Molecular Structure
  • Nanomedicine / methods*
  • Oxides / chemistry*
  • Photochemical Processes

Substances

  • Anti-Inflammatory Agents
  • Oxides
  • Graphite
  • Carbon Monoxide