Epidemiology of Community-Acquired Pneumonia Hospitalizations and Associated Complications Before and After the Implementation of the Heptavalent Pneumococcal Conjugate Vaccine in Athens, Greece

Theano Lagousi; Ioanna Papadatou; Ioannis Kopsidas; Elena Critselis; Maria Theodoridou; Vana Spoulou

doi:10.1093/jpids/pit088

Epidemiology of Community-Acquired Pneumonia Hospitalizations and Associated Complications Before and After the Implementation of the Heptavalent Pneumococcal Conjugate Vaccine in Athens, Greece

J Pediatric Infect Dis Soc. 2015 Sep;4(3):260-3. doi: 10.1093/jpids/pit088. Epub 2014 Jan 15.

Authors

Theano Lagousi¹, Ioanna Papadatou¹, Ioannis Kopsidas¹, Elena Critselis², Maria Theodoridou¹, Vana Spoulou¹

Affiliations

¹ First University Department of Pediatrics, "Aghia Sophia" Children's Hospital, National and Kapodistrian University of Athens School of Medicine, Greece.
² The Stavros Niarchos Foundation-Collaborative Center for Clinical Epidemiology and Outcomes Research, First and Second University Departments of Pediatrics, National and Kapodistrian University of Athens School of Medicine, Greece.

PMID: 26407430
DOI: 10.1093/jpids/pit088

Abstract

We determined the rates of community-acquired pneumonia (CAP)-associated hospitalizations and complications in Athens, over a period covering 4 years before and 4 years after the implementation of the 7-valent pneumococcal vaccine (PCV7) in Greece. PCV7 had no impact on pediatric CAP rates, whereas there was an increase in CAP-associated complications.

Keywords: children; pneumococcal vaccine; pneumonia.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Child
Child, Preschool
Community-Acquired Infections / epidemiology*
Community-Acquired Infections / prevention & control
Diagnostic Tests, Routine
Greece
Heptavalent Pneumococcal Conjugate Vaccine / administration & dosage*
Heptavalent Pneumococcal Conjugate Vaccine / immunology
Humans
Immunogenicity, Vaccine
Infant
Infant, Newborn
Pneumococcal Infections / epidemiology*
Pneumococcal Infections / immunology
Pneumococcal Infections / prevention & control*
Pneumonia / epidemiology*
Pneumonia / prevention & control
Retrospective Studies
Tertiary Care Centers

Substances

Heptavalent Pneumococcal Conjugate Vaccine