Acute Kidney Injury in the Surgical Patient

Crit Care Clin. 2015 Oct;31(4):705-23. doi: 10.1016/j.ccc.2015.06.007. Epub 2015 Jul 29.

Abstract

Perioperative acute kidney injury (AKI) is a common, morbid, and costly surgical complication. Current efforts to understand and manage AKI in surgical patients focus on prevention, mitigation of further injury when AKI has occurred, treatment of associated conditions, and facilitation of renal recovery. Lesser severity AKI is now understood to be much more common, and more morbid, than was previously thought. The ability to detect AKI within hours of onset would be helpful in protecting the kidney and in preserving renal function, and several imaging and biomarker modalities are currently being evaluated.

Keywords: Acute kidney injury; Chronic kidney disease; Complications; Perioperative.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acute Kidney Injury / diagnosis*
  • Acute Kidney Injury / etiology
  • Acute Kidney Injury / physiopathology
  • Acute Kidney Injury / prevention & control
  • Acute Kidney Injury / therapy*
  • Biomarkers / blood
  • Biomarkers / urine
  • Humans
  • Magnetic Resonance Imaging
  • Predictive Value of Tests
  • Renal Circulation
  • Risk Assessment / methods
  • Risk Factors
  • Surgical Procedures, Operative / adverse effects*
  • Ultrasonography, Doppler
  • Vascular Resistance

Substances

  • Biomarkers