Abstract
A 3-year-old neutered female poodle with a long history of dermatophytic skin disease was presented with lethargy, anorexia and progressive weight loss. Abdominal ultrasonography revealed markedly enlarged mesenteric lymph nodes and multiple hypoechoic foci in the spleen. Cytology of the mesenteric lymph nodes and spleen showed granulomatous inflammation with fungal organisms and negatively stained intracytoplasmic bacterial rods consistent with Mycobacteria spp. Based on culture, multiplex polymerase chain reaction and sequence analysis, the bacterium was identified as Mycobacterium avium subspecies hominissuis. Despite treatment with antibiotics, the dog's condition deteriorated, and it died approximately 3 weeks after first presentation.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Biopsy, Needle / veterinary
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Dog Diseases / diagnosis
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Dog Diseases / diagnostic imaging
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Dog Diseases / microbiology*
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Dog Diseases / pathology
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Dogs
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Female
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Granuloma / veterinary
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Lymph Nodes / diagnostic imaging
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Lymph Nodes / microbiology
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Lymph Nodes / pathology
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Multiplex Polymerase Chain Reaction / veterinary
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Mycobacterium avium Complex*
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Mycobacterium avium-intracellulare Infection / diagnosis
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Mycobacterium avium-intracellulare Infection / pathology
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Mycobacterium avium-intracellulare Infection / veterinary*
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Spleen / diagnostic imaging
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Spleen / microbiology
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Spleen / pathology
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Tuberculosis, Lymph Node / diagnosis
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Tuberculosis, Lymph Node / pathology
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Tuberculosis, Lymph Node / veterinary
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Tuberculosis, Splenic / diagnosis
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Tuberculosis, Splenic / pathology
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Tuberculosis, Splenic / veterinary
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Ultrasonography