Transient reduction in venous susceptibility during posterior reversible encephalopathy syndrome

Morgan Ollivier; Emmanuelle Wanono; Delphine Leclercq; Fanny Domont; Stéphanie Trunet; Didier Dormont; Anne Bertrand

doi:10.1016/j.jns.2015.09.359

Transient reduction in venous susceptibility during posterior reversible encephalopathy syndrome

J Neurol Sci. 2015 Nov 15;358(1-2):505-6. doi: 10.1016/j.jns.2015.09.359. Epub 2015 Sep 25.

Authors

Morgan Ollivier¹, Emmanuelle Wanono², Delphine Leclercq³, Fanny Domont², Stéphanie Trunet³, Didier Dormont⁴, Anne Bertrand⁵

Affiliations

¹ Department of Radiology, University Hospital Center, Hôpital de la Cavale-Blanche, F-29609 Brest Cedex, France; AP-HP, Pitié-Salpétrière Hospital, Department of Functional and Diagnostic Neuroradiology, F-75013 Paris, France.
² AP-HP, Pitié-Salpétrière Hospital, Department of Internal Medicine, F-75013 Paris, France.
³ AP-HP, Pitié-Salpétrière Hospital, Department of Functional and Diagnostic Neuroradiology, F-75013 Paris, France.
⁴ AP-HP, Pitié-Salpétrière Hospital, Department of Functional and Diagnostic Neuroradiology, F-75013 Paris, France; Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Inserm U 1127, CNRS UMR 7225, ICM, Inria Paris-Rocquencourt, F-75013, Paris, France.
⁵ AP-HP, Pitié-Salpétrière Hospital, Department of Functional and Diagnostic Neuroradiology, F-75013 Paris, France; Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Inserm U 1127, CNRS UMR 7225, ICM, Inria Paris-Rocquencourt, F-75013, Paris, France. Electronic address: [email protected].

PMID: 26434616
DOI: 10.1016/j.jns.2015.09.359

Abstract

We report a case of posterior reversible encephalopathy syndrome (PRES) in which followed-up MRI demonstrated a transient reduction in venous signal on initial SWAN images. The progressive normalization of venous signal on D10 and D40 imaging paralleled the progressive decrease of hyperperfusion on CBF images. Decreased venous susceptibility has never been reported in PRES; it relates most likely to a transient BOLD effect induced by brain hyperperfusion.

Keywords: Arterial spin labeling (ASL); Blood-oxygen level dependent (BOLD); Magnetic resonance imaging (MRI); Posterior reversible encephalopathy syndrome (PRES); SWAN; Susceptibility-weighted imaging (SWI); T2*.

Publication types

Case Reports
Letter

MeSH terms

Adult
Cerebral Veins / physiopathology*
Cerebrovascular Circulation / physiology*
Female
Humans
Magnetic Resonance Angiography
Magnetic Resonance Imaging / methods*
Posterior Leukoencephalopathy Syndrome / physiopathology*
Young Adult