Abstract
Water-soluble deep cavitands embedded in a supported lipid bilayer are capable of anchoring ATRP initiator molecules for the in situ synthesis of primary amine-containing polymethacrylate patches at the water:membrane interface. These polymers can be derivatized in situ to incorporate fluorescent reporters, allow selective protein recognition, and can be applied to the immobilization of nonadherent cells at the bilayer interface.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amines / chemistry
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Cell Line, Tumor
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Cells, Immobilized / chemistry
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Humans
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Lipid Bilayers / chemistry*
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Molecular Structure
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Polymethacrylic Acids / chemical synthesis*
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Polymethacrylic Acids / chemistry
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Proteins / analysis*
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Water / chemistry
Substances
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Amines
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Lipid Bilayers
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Polymethacrylic Acids
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Proteins
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Water
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polymethacrylic acid