Paraneoplastic skin disorders: a review

G Ital Dermatol Venereol. 2016 Feb;151(1):55-76. Epub 2015 Oct 6.

Abstract

Paraneoplastic disorders are manifestations of internal malignancies without the direct action of the tumor. Its pathogenesis involves production of substances that interfere with cellular activity of distant tissues. Paraneoplasias may be the first sign of cancer, and clinicians should be familiarized with its manifestations in order to perform an early diagnosis of the underlying neoplasm. The aim of this review was to describe most common paraneoplastic skin diseases.

Publication types

  • Review

MeSH terms

  • Acanthosis Nigricans / diagnosis
  • Acanthosis Nigricans / etiology
  • Body Mass Index
  • Brazil / epidemiology
  • Dermatitis, Exfoliative / diagnosis
  • Dermatitis, Exfoliative / etiology
  • Dermatomyositis / diagnosis
  • Dermatomyositis / etiology
  • Early Detection of Cancer
  • Humans
  • Hypertrichosis / diagnosis
  • Hypertrichosis / etiology
  • Insulin Resistance
  • Neoplasms / complications
  • Neoplasms / diagnosis
  • Obesity / complications
  • Paraneoplastic Syndromes / complications*
  • Paraneoplastic Syndromes / diagnosis*
  • Paraneoplastic Syndromes / epidemiology
  • Risk Factors
  • Skin Diseases / diagnosis*
  • Skin Diseases / epidemiology
  • Skin Diseases / etiology*