Impact of therapy in a cohort of unselected children with Down Syndrome-associated Acute Lymphoblastic Leukaemia

Br J Haematol. 2016 Sep;174(6):983-5. doi: 10.1111/bjh.13817. Epub 2015 Oct 12.
No abstract available

Keywords: Down syndrome; acute leukaemia; therapy-related mortality; treatment.

Publication types

  • Letter

MeSH terms

  • Anthracyclines / therapeutic use
  • Child
  • Child, Preschool
  • Cohort Studies
  • Down Syndrome / complications*
  • Female
  • Humans
  • Male
  • Methotrexate / administration & dosage
  • Methotrexate / toxicity
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • Survival Analysis
  • Treatment Outcome

Substances

  • Anthracyclines
  • Methotrexate