PBP2a substitutions linked to ceftaroline resistance in MRSA isolates from the UK

J Antimicrob Chemother. 2016 Jan;71(1):268-9. doi: 10.1093/jac/dkv317. Epub 2015 Oct 12.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Substitution
  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics*
  • Ceftaroline
  • Cephalosporins / pharmacology*
  • Humans
  • Methicillin-Resistant Staphylococcus aureus / drug effects*
  • Methicillin-Resistant Staphylococcus aureus / genetics
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification
  • Microbial Sensitivity Tests
  • Penicillin-Binding Proteins / genetics*
  • Staphylococcal Infections / microbiology
  • United Kingdom
  • beta-Lactam Resistance*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Cephalosporins
  • Penicillin-Binding Proteins
  • mecA protein, Staphylococcus aureus