A randomised controlled trial of bilateral dual transversus abdominis plane blockade for laparoscopic appendicectomy

Anaesthesia. 2015 Dec;70(12):1395-400. doi: 10.1111/anae.13234. Epub 2015 Oct 14.

Abstract

We investigated the effects of pre-operative ultrasound-guided bilateral dual transversus abdominis plane blocks on pain when sitting up and pain at rest after laparoscopic appendicectomy. We allocated 28 participants to injection with 60 ml ropivacaine 0.375% and 28 participants to 60 ml isotonic saline. The median (IQR [range]) cumulative pain scores during the first 12 postoperative hours were less after ropivacaine than saline (maximum 120): on sitting, 34 (19-46 [0-59]) vs 50 (30-59 [0-97]), respectively, p = 0.009; and at rest, 25 (10-33 [0-49]) vs 31 (24-43 [0-72]), respectively, p = 0.035. There were no differences in morphine consumption, nausea, vomiting, time in recovery or time to walk.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdominal Muscles / innervation*
  • Adult
  • Amides / pharmacology
  • Appendectomy / methods*
  • Female
  • Humans
  • Laparoscopy / methods*
  • Male
  • Middle Aged
  • Morphine / administration & dosage
  • Nerve Block / methods*
  • Ropivacaine

Substances

  • Amides
  • Morphine
  • Ropivacaine