Successful Resolution of Gastric Outlet Obstruction Caused by Pancreatic Pseudocyst or Walled-Off Necrosis After Acute Pancreatitis: The Role of Percutaneous Catheter Drainage

Pancreas. 2015 Nov;44(8):1290-5. doi: 10.1097/MPA.0000000000000429.

Abstract

Objective: Delayed gastric emptying (DGE) in patients with acute pancreatitis (AP) can be caused by gastroparesis or gastric outlet obstruction, which may occur when pancreatic pseudocyst (PP) or walled-off necrosis (WON) compresses the stomach. The aim of the study was to explore a proper surgical treatment.

Methods: From June 2010 to June 2013, 25 of 148 patients with AP suffered DGE. Among them, 12 were caused by gastroparesis, 1 was a result of obstruction from a Candida albicans plug, and 12 were gastric outlet obstruction (GOO) compressed by PP (n = 8) or WON (n = 4), which were treated by percutaneous catheter drainage (PCD).

Results: All 12 cases of compressing GOO achieved resolution by PCD after 6 [1.86] and 37.25 [12.02] days for PP and WON, respectively. Five cases developed intracystic infection, 3 cases had pancreatic fistulae whereas 2 achieved resolution and 1 underwent a pseudocyst jejunostomy.

Conclusions: Gastric outlet obstruction caused by a PP or WON is a major cause of DGE in patients with AP. Percutaneous catheter drainage with multiple sites, large-bore tubing, and lavage may be a good therapy due to high safety and minimal invasiveness.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Catheters
  • Drainage / adverse effects
  • Drainage / methods*
  • Gastric Emptying
  • Gastric Outlet Obstruction / etiology
  • Gastric Outlet Obstruction / physiopathology
  • Gastric Outlet Obstruction / surgery*
  • Gastroparesis / diagnosis
  • Gastroparesis / physiopathology
  • Humans
  • Jejunostomy
  • Necrosis / complications
  • Pancreatic Fistula / etiology
  • Pancreatic Fistula / surgery
  • Pancreatic Pseudocyst / complications*
  • Pancreatitis / complications*
  • Treatment Outcome