Abstract
To analyze the molecular mechanisms of cross-host transmission of the Aleutian mink disease vi rus (ADV), the hypervariable region fragment of the VP2 gene of the ADV in Jilin Province (China) was amplified. Sequencing analyses showed diversity at residue 174 by comparison with other VP2 genes in GenBank. The phylogenetic tree indicated that the ADV-JL strain had a close relationship with the highly pathogenic strain from Denmark: ADV-K. Results implied that residue 174 may be associated with ADV infectivity.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Aleutian Mink Disease / virology*
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Aleutian Mink Disease Virus / chemistry
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Aleutian Mink Disease Virus / classification
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Aleutian Mink Disease Virus / genetics*
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Aleutian Mink Disease Virus / isolation & purification
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Amino Acid Sequence
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Animals
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Capsid Proteins / chemistry
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Capsid Proteins / genetics*
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China
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Mink
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Molecular Sequence Data
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Phylogeny
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Sequence Alignment
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Sequence Analysis
Substances
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Capsid Proteins
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VP2 protein, Aleutian mink disease virus