Evaluation of the effects of silicone implants on the breast parenchyma

Aesthet Surg J. 2015 Nov;35(8):929-35. doi: 10.1093/asj/sjv120.

Abstract

Background: Despite being the cosmetic procedure most performed worldwide, there are still few objective measurements of postoperative volumetric analysis of breast augmentation available in the literature.

Objective: The aim of this study was to evaluate volumetric changes in the breast parenchyma after the placement of silicone implants in the subglandular plane.

Methods: Thirty-four women were randomly allocated to the intervention group (n = 24), who underwent breast augmentation in the subglandular plane, or to the control group (n = 10), who received no intervention. Volumetric magnetic resonance imaging was performed at inclusion, and after 6 and 12 months in all participants. The non-parametric Friedman's test was used for statistical analysis.

Results: There was a significant reduction in glandular volume (mean, 22%) at 12 months postoperatively in patients who underwent breast augmentation.

Conclusions: Breast augmentation caused reduction in the volume of the breast parenchyma.

Level of evidence: 3 Therapeutic.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Brazil
  • Breast / anatomy & histology*
  • Breast Implantation / adverse effects
  • Breast Implantation / methods*
  • Breast Implants / adverse effects*
  • Female
  • Follow-Up Studies
  • Humans
  • Longitudinal Studies
  • Magnetic Resonance Imaging / methods
  • Mammography / methods
  • Organ Size / physiology
  • Preoperative Care / methods
  • Prospective Studies
  • Prosthesis Design
  • Prosthesis Failure
  • Reference Values
  • Risk Assessment
  • Silicone Gels / adverse effects
  • Silicone Gels / pharmacology*
  • Time Factors
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome
  • Young Adult

Substances

  • Silicone Gels