Abstract
•22q11DS offers a compelling model to understand the neural substrates of attentional dysfunction.•First study directly comparing neural function in 22q11DS vs. ADHD patients•22q11DS and ADHD patients show a shared deficit in RI-related activation.•ADHD patients showed greater activity in the middle frontal gyrus than 22q11DS during RI.•Neural activity is inversely correlated with self-reported Cognitive Impulsivity in 22q11DS.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Adolescent
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Adult
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Analysis of Variance
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Attention Deficit Disorder with Hyperactivity / complications*
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Attention Deficit Disorder with Hyperactivity / pathology
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Brain / blood supply
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Brain / pathology*
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Brain Mapping*
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DiGeorge Syndrome / complications*
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Female
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Follow-Up Studies
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Humans
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Image Processing, Computer-Assisted
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Impulsive Behavior / physiology*
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Inhibition, Psychological*
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Magnetic Resonance Imaging
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Male
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Neuropsychological Tests
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Oxygen / blood
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Psychiatric Status Rating Scales
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Statistics as Topic
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Young Adult