Design and interpretation of clinical research studies in oral medicine: a brief review

J C Atkinson; D B Clark

doi:10.1111/odi.12385

Design and interpretation of clinical research studies in oral medicine: a brief review

Oral Dis. 2016 Mar;22(2):87-92. doi: 10.1111/odi.12385. Epub 2015 Dec 18.

Authors

J C Atkinson¹, D B Clark²

Affiliations

¹ Center for Clinical Research, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.
² Behavioral and Social Sciences Research Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

Abstract

The objective of this short review is to help researchers improve the designs of their clinical studies. Also included is a discussion of the level of evidence provided by the various clinical research study designs.

Keywords: clinical research; epidemiology; oral medicine.

Published 2015. This article is a U.S. Government work and is in the public domain in the USA.

Publication types

Review

MeSH terms

Biomedical Research / methods*
Clinical Studies as Topic / methods*
Humans
Oral Medicine*
Research Design*

Grants and funding

Z99 DE999999/Intramural NIH HHS/United States