Magnetic resonance imaging findings of undifferentiated carcinoma with osteoclast-like giant cells of pancreas

Kyung Yoon Yang; Joon-Il Choi; Moon Hyung Choi; Michael Yong Park; Sung Eun Rha; Jae Young Byun; Eun Sun Jung; Chandana Lall

doi:10.1016/j.clinimag.2015.09.013

Magnetic resonance imaging findings of undifferentiated carcinoma with osteoclast-like giant cells of pancreas

Clin Imaging. 2016 Jan-Feb;40(1):148-51. doi: 10.1016/j.clinimag.2015.09.013. Epub 2015 Sep 24.

Authors

Kyung Yoon Yang¹, Joon-Il Choi², Moon Hyung Choi¹, Michael Yong Park¹, Sung Eun Rha¹, Jae Young Byun¹, Eun Sun Jung³, Chandana Lall⁴

Affiliations

¹ Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, the Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, Republic of Korea.
² Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, the Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, Republic of Korea. Electronic address: [email protected].
³ Department of Pathology, Seoul St. Mary's Hospital, College of Medicine, the Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, Republic of Korea.
⁴ Department of Radiological Sciences, University of California, Irvine, 101 The City Drive South, Orange, CA, 92868, the United States of America.

PMID: 26520702
DOI: 10.1016/j.clinimag.2015.09.013

Abstract

Undifferentiated carcinoma with osteoclast-like giant cells is a rare pancreatic and periampullary neoplasm with less than 50 cases reported in the literature. Pathologically, this tumor mimics a giant cell tumor in bones. We report a case of undifferentiated carcinoma with osteoclast-like giant cells in a 55-year-old man presenting as a pancreatic mass with associated regional and distant lymphadenopathy. On T1- and T2-weighted images, the mass shows dark signal intensity which was atypical for a pancreatic adenocarcinoma.

Keywords: CD68; Magnetic resonance imaging; Pancreas; Undifferentiated carcinoma with osteoclast-like giant cells.

Publication types

Case Reports

MeSH terms

Adenocarcinoma / diagnostic imaging
Adenocarcinoma / pathology*
Contrast Media
Diagnosis, Differential
Giant Cells / diagnostic imaging
Giant Cells / pathology*
Humans
Image Enhancement
Magnetic Resonance Imaging*
Male
Middle Aged
Organometallic Compounds
Osteoclasts / diagnostic imaging
Osteoclasts / pathology*
Pancreas / diagnostic imaging
Pancreas / pathology*
Pancreatic Neoplasms / diagnostic imaging
Pancreatic Neoplasms / pathology*
Tomography, X-Ray Computed
Ultrasonography

Substances

Contrast Media
Organometallic Compounds
gadobutrol