To the limit of extreme malnutrition

Nutrition. 2016 Jan;32(1):146-8. doi: 10.1016/j.nut.2015.08.024. Epub 2015 Sep 28.

Abstract

Extreme malnutrition with body mass index (BMI) as low as 10 kg/m(2) is not uncommon in anorexia nervosa, with survival enabled through complex metabolic adaptations. In contrast, outcomes from hunger strikes and famines are usually fatal after weight loss to about 40% below expected body weight, corresponding to BMI 12 to 13 kg/m(2) in adults. Thus, many years of adaptation in adolescent-onset anorexia nervosa, supported by supplements of vitamins and treatment of intercurrent diseases, may allow survival at a much lower BMI. However, in the literature only a few cases of survival in patients with BMI <9 kg/m(2) have been described. We report on the case of a 29-y-old woman who was successfully treated in a specialized unit. She had a BMI of 7.8 kg/m(2). To our knowledge, this level of extreme malnutrition has not previously been reported. The present case emphasizes the importance of adherence to guidelines to decrease refeeding complications.

Keywords: Anorexia nervosa; Eating disorder; Refeeding syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anorexia Nervosa / complications*
  • Body Mass Index*
  • Body Weight*
  • Female
  • Humans
  • Malnutrition / diet therapy
  • Malnutrition / etiology*
  • Refeeding Syndrome / prevention & control
  • Severity of Illness Index*