Hemorrhage in astroblastoma: An unusual manifestation of an extremely rare entity

J Clin Neurosci. 2016 Mar:25:147-50. doi: 10.1016/j.jocn.2015.05.058. Epub 2015 Nov 4.

Abstract

Astroblastoma is a rare tumor of glial origin with characteristics of both astrocytoma and ependymoma. It is usually seen in children and young adults, and is peripherally located, well circumscribed, of solid-cystic composition and with heterogeneous contrast enhancement. Histopathology reveals perivascular pseudorosette formation and thick hyalinised vessels. Hemorrhage in astroblastoma is unusual and rarely described in literature. We report two patients with astroblastoma who presented with hemorrhage and discuss the natural history, radiological findings, pathophysiology of hemorrhage and histopathological characteristics. We emphasize the importance of early suspicion in peripherally located lesions with bleeding.

Keywords: Anaplastic; Astroblastoma; Hemorrhage.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms / complications
  • Brain Neoplasms / pathology*
  • Cerebral Hemorrhage / etiology*
  • Child
  • Female
  • Humans
  • Male
  • Neoplasms, Neuroepithelial / complications
  • Neoplasms, Neuroepithelial / pathology*