[Study of the immunization coverage determinants of vaccination campaign against meningococcal A meningitis in Burkina Faso]

Rev Epidemiol Sante Publique. 2015 Dec;63(6):347-53. doi: 10.1016/j.respe.2015.09.006. Epub 2015 Nov 5.
[Article in French]

Abstract

Background: Sub-Saharan Africa countries suffer from repeated and explosive epidemics of meningitis mainly due to Neisseria meningitidis A. In December 2010, Burkina Faso organized a vaccination campaign with MenAfriVac® for people aged 1-29 years old. The objective of this study was to analyze the determinants of immunization coverage.

Methods: We used a cross-sectional survey by cluster sampling in two stages, descriptive and analytical, conducted in the region of "Boucle du Mouhoun". Data were collected during a home interview. The dependent variable was vaccination status and the independent variables included individual and household characteristics but also the means of communication used during the campaign. A logistic regression model was used to estimate the risk of being vaccinated using the 'Survey' Package (SVYGLM) of R.

Results: Two thousand and twenty-five people were included with a 93.5 % estimated coverage. Factors associated with high vaccination coverage are rural areas (ORa=2.53 [1.53-4.17]) and smaller households (ORa=3.06 [1.36-6.91]). The risk of being vaccinated was lower for persons from salaried heads of household (ORa=0.14 [0.02-0.87]) versus farmers, persons informed by religious and traditional leaders (ORa=0.25 [0.11-0.57]) or family and friends (ORa=0.51 [0.29-0.9]) versus community mobilizers.

Conclusion: The coverage recorded is sufficient to provide community immunity. However, a part of the target population could not benefit from vaccination due to lack of information. Particular emphasis should be placed on large urban families using community mobilizers.

Keywords: Burkina Faso; Couverture vaccinale; Determinants; Déterminants; Immunization coverage; Meningitis; Méningites.

MeSH terms

  • Adolescent
  • Adult
  • Burkina Faso / epidemiology
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Disease Outbreaks / prevention & control
  • Female
  • Humans
  • Infant
  • Male
  • Meningitis, Meningococcal / epidemiology*
  • Meningitis, Meningococcal / prevention & control*
  • Meningococcal Vaccines / therapeutic use*
  • Neisseria meningitidis / immunology
  • Vaccination / statistics & numerical data*
  • Young Adult

Substances

  • MenAfriVac
  • Meningococcal Vaccines