Abstract
This review deals with two topics: (1) the effects of fibronectin and laminin on neurite growth and the molecular mechanisms of these effects, and (2) isolation and properties of the adhesive molecule p30. This novel molecule is an abundant heparin-binding protein in perinatal rat brain, and is suggested to have a role in neuronal growth.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Cell Adhesion
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Extracellular Matrix / metabolism
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Fibronectins / metabolism
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Fibronectins / pharmacology
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Gangliosides / metabolism
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Laminin / metabolism
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Laminin / pharmacology
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Membrane Proteins / isolation & purification*
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Neuroblastoma / pathology
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Neurons / cytology
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Neurons / drug effects
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Neurons / metabolism*
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Tumor Cells, Cultured / drug effects
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Tumor Cells, Cultured / pathology
Substances
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Fibronectins
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Gangliosides
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Laminin
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Membrane Proteins