[Neonatal neuroblastoma complicated with a threatening tumoral hepatomegaly treated by irradiation: No sequel 20 years later]

M Doré; M-A Mahé; N Corradini; C Demoor-Goldschmidt

doi:10.1016/j.canrad.2015.05.030

[Neonatal neuroblastoma complicated with a threatening tumoral hepatomegaly treated by irradiation: No sequel 20 years later]

Cancer Radiother. 2015 Dec;19(8):749-51. doi: 10.1016/j.canrad.2015.05.030. Epub 2015 Nov 10.

[Article in French]

Authors

M Doré¹, M-A Mahé², N Corradini³, C Demoor-Goldschmidt⁴

Affiliations

¹ Service de radiothérapie, institut de cancérologie de l'Ouest René-Gauducheau, boulevard Jacques-Monod, 44800 Saint-Herblain, France.
² Service de radiothérapie, institut de cancérologie de l'Ouest René-Gauducheau, boulevard Jacques-Monod, 44800 Saint-Herblain, France; Faculté de médecine de Nantes, université de Nantes, 1, rue Gaston-Veil, 44000 Nantes, France.
³ Service d'oncologie pédiatrique, CHU de Nantes, quai Moncusu, 44000 Nantes, France; Suivi à long terme, institut de cancérologie de l'Ouest René-Gauducheau, boulevard Jacques-Monod, 44800 Saint-Herblain, France.
⁴ Service de radiothérapie, institut de cancérologie de l'Ouest René-Gauducheau, boulevard Jacques-Monod, 44800 Saint-Herblain, France; Faculté de médecine de Nantes, université de Nantes, 1, rue Gaston-Veil, 44000 Nantes, France; Suivi à long terme, institut de cancérologie de l'Ouest René-Gauducheau, boulevard Jacques-Monod, 44800 Saint-Herblain, France. Electronic address: [email protected].

PMID: 26563872
DOI: 10.1016/j.canrad.2015.05.030

Abstract

In this article, we report the case of a newborn who presented a life-threatening hepatomegaly with respiratory distress at 12 days of life, complicating a metastatic neuroblastoma. Low-dose liver radiotherapy was performed in emergency in order to decompress. Chemotherapy has also been delivered due to a tumoral relapse 1 month after radiotherapy. After a follow-up of 20 years, this young woman is still in complete remission, with no long-term sequelae.

Keywords: Child; Enfant; Long-term follow-up; Neuroblastoma; Neuroblastome; Newborn; Nouveau-né; Pepper; Radiotherapy; Radiothérapie; Suivi à long terme; Survival; Survivant.

Publication types

Case Reports
English Abstract

MeSH terms

Female
Follow-Up Studies
Hepatomegaly / etiology*
Hepatomegaly / radiotherapy*
Humans
Infant, Newborn
Liver Neoplasms / complications*
Liver Neoplasms / radiotherapy*
Neuroblastoma / complications*
Neuroblastoma / radiotherapy*
Remission Induction
Severity of Illness Index
Time Factors
Young Adult