Comparison of Antibiotic Susceptibility Patterns of Bacterial Isolates Based on Time From Hospitalization and Culture Source: Implications for Hospital Antibiograms

Yaakov Dickstein; Yuval Geffen; Leonard Leibovici; Mical Paul

doi:10.1017/ice.2015.258

Comparison of Antibiotic Susceptibility Patterns of Bacterial Isolates Based on Time From Hospitalization and Culture Source: Implications for Hospital Antibiograms

Infect Control Hosp Epidemiol. 2016 Feb;37(2):212-4. doi: 10.1017/ice.2015.258. Epub 2015 Nov 13.

Authors

Yaakov Dickstein¹, Yuval Geffen², Leonard Leibovici³, Mical Paul¹

Affiliations

¹ 1Division of Infectious Diseases,Rambam Health Care Campus,Haifa,Israel.
² 2Medical Microbiology Laboratory,Rambam Health Care Campus,Haifa,Israel.
³ 3Medicine E, Rabin Medical Center,Beilinson Hospital, Sackler Faculty of Medicine,Tel-Aviv University,Tel-Aviv,Israel.

PMID: 26564427
DOI: 10.1017/ice.2015.258

Abstract

We assessed the effects of time from hospitalization and culture source on bacterial susceptibility profiles. Increasing resistance correlated with increasing time from hospitalization for all bacterial groups, with 7 days in hospital representing the best time point for dichotomizing susceptibility rates rather than 48 hours. Antibiograms based on isolates from any source best represented susceptibility profiles.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Acinetobacter / drug effects*
Anti-Bacterial Agents / pharmacology*
Cross Infection / microbiology
Drug Resistance, Bacterial
Enterobacteriaceae / drug effects*
Enterococcus / drug effects*
Hospitals, University
Humans
Israel
Length of Stay
Microbial Sensitivity Tests
Pseudomonas aeruginosa / drug effects*
Staphylococcus aureus / drug effects*
Time Factors

Substances

Anti-Bacterial Agents