Recurrent Septic Arthritis Due to Achromobacter xylosoxidans in a Patient With Granulomatosis With Polyangiitis

Payal K Patel; Arvind von Keudell; Philipp Moroder; Paul Appleton; Robin Wigmore; Edward K Rodriguez

doi:10.1093/ofid/ofv145

Recurrent Septic Arthritis Due to Achromobacter xylosoxidans in a Patient With Granulomatosis With Polyangiitis

Open Forum Infect Dis. 2015 Sep 28;2(4):ofv145. doi: 10.1093/ofid/ofv145. eCollection 2015 Dec.

Authors

Payal K Patel¹, Arvind von Keudell², Philipp Moroder³, Paul Appleton², Robin Wigmore⁴, Edward K Rodriguez²

Affiliations

¹ Department of Internal Medicine, Division of Infectious Diseases , University of Michigan Medical School ; Department of Medicine, Division of Infectious Diseases , Veterans Affairs Ann Arbor Healthcare System , Michigan.
² Department of Orthopedics, Beth Israel Deaconess Medical Center , Harvard Medical School , Boston, Massachusetts.
³ Department of Traumatology , Paracelsus Medical University , Salzburg , Austria.
⁴ Department of Medicine, Division of Infectious Diseases , Beth Israel Deaconess Medical Center, Harvard Medical School , Lowry Medical Office Building, Boston, Massachusetts.

Abstract

We report a case of recurrent Achromobacter xylosoxidans infections including bacteremia, sepsis, septic joints and endocarditis in a 72 year old female with granulomatosis with polyangiitis. Achromobacter xylosoxidans is a gram negative bacteria increasingly identified in immunocompromised patients. Surgical and medical therapy may need to be combined.

Keywords: Achromobacter; gram negative; native joint; septic arthritis; virulence.