Anthracofibrosis Manifesting as False-Positive Iodine Accumulation in a Patient With Recent History of Thyroid Carcinoma

Clin Nucl Med. 2016 Apr;41(4):336-7. doi: 10.1097/RLU.0000000000001074.

Abstract

A 33-year-old Indonesian woman presented for follow-up after a recent history of papillary thyroid carcinoma treated with total thyroidectomy and radioiodine therapy. A 131I whole-body scintigraphy showed an elongated iodine accumulation in the right hemithorax. On suspicion of pulmonary metastasis, further diagnostics with 124I PET/CT showed thickening of the bronchial wall and retention of secretion in a middle lobe bronchus. Bronchoscopy and histology allowed a diagnosis of stenosing anthracofibrosis with chronic inflammatory changes.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bronchi / diagnostic imaging*
  • Bronchi / pathology
  • Carcinoma / radiotherapy*
  • Carcinoma, Papillary
  • False Positive Reactions
  • Female
  • Fibrosis / diagnostic imaging
  • Humans
  • Iodine Radioisotopes / adverse effects*
  • Iodine Radioisotopes / therapeutic use
  • Multimodal Imaging
  • Positron-Emission Tomography
  • Radiopharmaceuticals / adverse effects*
  • Radiopharmaceuticals / therapeutic use
  • Thyroid Cancer, Papillary
  • Thyroid Neoplasms / pathology
  • Thyroid Neoplasms / radiotherapy*
  • Tomography, X-Ray Computed

Substances

  • Iodine Radioisotopes
  • Radiopharmaceuticals