Successful elimination of a lethal wildlife infectious disease in nature

Biol Lett. 2015 Nov;11(11):20150874. doi: 10.1098/rsbl.2015.0874.

Abstract

Methods to mitigate the impacts of emerging infectious diseases affecting wildlife are urgently needed to combat loss of biodiversity. However, the successful mitigation of wildlife pathogens in situ has rarely occurred. Indeed, most strategies for combating wildlife diseases remain theoretical, despite the wealth of information available for combating infections in livestock and crops. Here, we report the outcome of a 5-year effort to eliminate infection with Batrachochytrium dendrobatidis affecting an island system with a single amphibian host. Our initial efforts to eliminate infection in the larval reservoir using a direct application of an antifungal were successful ex situ but infection returned to previous levels when tadpoles with cleared infections were returned to their natal sites. We subsequently combined antifungal treatment of tadpoles with environmental chemical disinfection. Infection at four of the five pools where infection had previously been recorded was eradicated, and remained so for 2 years post-application.

Keywords: Alytes muletensis; Batrachochytrium dendrobatidis; Mallorca; chytridiomycosis; mitigation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Wild
  • Antifungal Agents / administration & dosage
  • Anura / microbiology*
  • Chytridiomycota / drug effects*
  • Disinfectants
  • Islands
  • Itraconazole / administration & dosage
  • Larva / drug effects
  • Larva / microbiology
  • Mycoses / drug therapy
  • Mycoses / veterinary*
  • Peroxides
  • Ponds / microbiology
  • Spain
  • Sulfuric Acids

Substances

  • Antifungal Agents
  • Disinfectants
  • Peroxides
  • Sulfuric Acids
  • monoperoxysulfate
  • Itraconazole