The Role of Protein Modelling in Predicting the Disease Severity of Cystinuria

Eur Urol. 2016 Mar;69(3):543-4. doi: 10.1016/j.eururo.2015.10.039. Epub 2015 Nov 14.

Authors

Kathie Alexina Wong¹, Mark Wass², Kay Thomas³

Affiliations

¹ Urology Centre, Guy's and St. Thomas' NHS Foundation Trust, London, SE1 9RT, UK. Electronic address: [email protected].
² School of Biosciences, University of Kent, Canterbury Kent, UK.
³ Urology Centre, Guy's and St. Thomas' NHS Foundation Trust, London, SE1 9RT, UK.

PMID: 26589650
DOI: 10.1016/j.eururo.2015.10.039

No abstract available

Publication types

Letter

MeSH terms

Amino Acid Transport Systems, Basic / chemistry*
Amino Acid Transport Systems, Basic / genetics
Amino Acid Transport Systems, Basic / metabolism
Amino Acid Transport Systems, Neutral / chemistry*
Amino Acid Transport Systems, Neutral / genetics
Amino Acid Transport Systems, Neutral / metabolism
Cystinuria / diagnosis*
Cystinuria / genetics
Cystinuria / metabolism
Genetic Predisposition to Disease
Humans
Models, Molecular*
Mutation, Missense
Phenotype
Predictive Value of Tests
Protein Conformation
Severity of Illness Index
Structure-Activity Relationship

Substances

Amino Acid Transport Systems, Basic
Amino Acid Transport Systems, Neutral
SLC3A1 protein, human
SLC7A9 protein, human