A first reported case of clear cell carcinoma associated with delayed extrusion of midurethral tape

Int Urogynecol J. 2016 Mar;27(3):377-80. doi: 10.1007/s00192-015-2876-5. Epub 2015 Nov 20.

Abstract

We present the first reported case of clear cell carcinoma associated with a midurethral tape (MUT), the possible hypotheses and the management pitfalls we encountered. We report a 58-year-old woman who presented with symptoms of urinary tract infection and acute retention of urine associated with vaginal tape exposure 10 years after placement of an inside-out transobturator tape. She subsequently had a partial transobturator tape excision and a diagnostic cystoscopy, which revealed inflammatory changes within the urethra. Postoperatively, her symptoms persisted and the vaginal epithelium healed poorly. A biopsy of the friable tissue reported clear cell carcinoma. Imaging showed a locally invasive periurethral mass and bony and lymphatic metastases. This was treated with palliative radiation therapy. She was still receiving palliative care 5 months after the initial surgery.

Keywords: Clear cell carcinoma; Midurethral tape; Tape extrusion; Transobturator tape.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Clear Cell / etiology*
  • Female
  • Humans
  • Middle Aged
  • Suburethral Slings / adverse effects*
  • Vaginal Neoplasms / etiology*