Four amino acid exchanges located in the alpha-2 domain specify the novel HLA-B*50:20 allele

Tissue Antigens. 2015 Dec;86(6):453-5. doi: 10.1111/tan.12697.

Authors

P S A Becker¹, E Seifried¹, C Seidl¹

Affiliation

¹ Institute for Transfusion Medicine and Immunohaematology, German Red Cross Blood Donor Service Baden-Wuerttemberg-Hessen, Frankfurt, Germany.

PMID: 26593755
DOI: 10.1111/tan.12697

Abstract

HLA-B*50:20 contains seven nucleotide substitutions leading to four amino acid changes in the alpha-2 domain.

Keywords: HLA-B*50; human leukocyte antigen-B; sequence-based typing.

© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Amino Acid Substitution
Base Sequence
Exons / genetics
Genes, MHC Class II*
HLA-B Antigens / chemistry*
HLA-B Antigens / genetics
Humans
Models, Molecular
Molecular Sequence Data
Protein Conformation
Protein Structure, Tertiary
Sequence Alignment
Sequence Homology, Nucleic Acid

Substances

HLA-B Antigens