Every little piece counts: the many faces of tRNA transcripts

Transcription. 2015;6(4):74-7. doi: 10.1080/21541264.2015.1093064.

Abstract

For over half a century, tRNAs have been exclusively known as decoders of genomic information. However, recent reports evidenced that tRNA transcripts are also bearers of functional RNAs, which are able to execute various tasks through an array of mechanisms. Here, we succinctly review the diversity and functions of RNAs deriving from tRNA loci.

Keywords: 3′ETS; ITS; TLR; junk RNA; regulatory RNA; tRFs; tRNA; tRNA halves.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anticodon / genetics*
  • Base Sequence
  • Humans
  • Models, Genetic
  • Nucleic Acid Conformation
  • RNA Precursors / genetics*
  • RNA Processing, Post-Transcriptional
  • RNA, Transfer / chemistry
  • RNA, Transfer / genetics*
  • Transcription, Genetic*

Substances

  • Anticodon
  • RNA Precursors
  • RNA, Transfer