Spectral-Domain Optical Coherence Tomography of Polypoidal Choroidal Vasculopathy Associated With Benign Choroidal Nevus

Ophthalmic Surg Lasers Imaging Retina. 2015 Nov-Dec;46(10):1062-4. doi: 10.3928/23258160-20151027-15.

Abstract

Two cases of polypoidal choroidal vasculopathy (PCV) complicating benign choroidal nevus and their tomographic features at spectral-domain optical coherence tomography (SD-OCT) are reported. Two eyes with choroidal nevus and associated subretinal fluid underwent complete ophthalmological examination, SD-OCT, fundus fluorescein angiography, and indocyanine green angiography (ICGA). SD-OCT and ICGA confirmed the diagnosis of PCV in both cases. Ophthalmologists should be aware of this rare combination between choroidal nevus and PCV. If a choroidal nevus presents with subretinal fluid, this does not always herald malignant transformation, and PCV should be ruled out so that the correct treatment can be planned.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiogenesis Inhibitors / therapeutic use
  • Capillary Permeability
  • Choroid Neoplasms / diagnosis*
  • Choroid Neoplasms / drug therapy
  • Choroidal Neovascularization / diagnosis*
  • Choroidal Neovascularization / drug therapy
  • Exudates and Transudates
  • Female
  • Fluorescein Angiography
  • Humans
  • Male
  • Nevus, Pigmented / diagnosis*
  • Nevus, Pigmented / drug therapy
  • Photochemotherapy
  • Polyps / diagnosis*
  • Polyps / drug therapy
  • Ranibizumab / therapeutic use
  • Retinal Detachment / diagnosis
  • Retinal Pigment Epithelium / pathology
  • Tomography, Optical Coherence*
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors
  • Visual Acuity

Substances

  • Angiogenesis Inhibitors
  • VEGFA protein, human
  • Vascular Endothelial Growth Factor A
  • Ranibizumab