A case of bipolar and relapsing cerebrovascular hemorrhages with hypertension is reported in a 7 year-old Gabonese girl. These strokes were the first sign of a sickle cell disease. Mechanisms of cerebral hemorrhages in sickle cell disease are reviewed and similarities with the "hypertension, convulsion and cerebral hemorrhage after transfusions "syndrome reported by Wasi et al. in thalassemic patients are underlined.