A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial

Am J Respir Crit Care Med. 2015 Dec 1;192(11):1389-92. doi: 10.1164/rccm.201506-1193LE.
No abstract available

Publication types

  • Clinical Trial, Phase I
  • Clinical Trial, Phase II
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Intranasal
  • Adolescent
  • Adult
  • Cystic Fibrosis / genetics
  • Cystic Fibrosis / therapy*
  • Cystic Fibrosis Transmembrane Conductance Regulator / administration & dosage*
  • Cystic Fibrosis Transmembrane Conductance Regulator / genetics*
  • Female
  • Gene Transfer Techniques
  • Genetic Therapy*
  • Humans
  • Liposomes
  • Male
  • Middle Aged
  • Nebulizers and Vaporizers
  • Young Adult

Substances

  • Liposomes
  • Cystic Fibrosis Transmembrane Conductance Regulator