Recurrent Nocardia Sepsis in a Patient With Sickle Cell Anemia Receiving Continuous Deferoxamine

Jacob M Wessler; Daniel J Adams; Anjali N Kunz; Janiine G Babcock; Kip R Hartman

doi:10.1093/jpids/pit038

Recurrent Nocardia Sepsis in a Patient With Sickle Cell Anemia Receiving Continuous Deferoxamine

J Pediatric Infect Dis Soc. 2014 Sep;3(3):e35-7. doi: 10.1093/jpids/pit038. Epub 2013 Jul 23.

Authors

Jacob M Wessler¹, Daniel J Adams², Anjali N Kunz³, Janiine G Babcock⁴, Kip R Hartman⁴

Affiliations

¹ Department of Pediatric Hematology/Oncology.
² Department of Pediatric Infectious Diseases, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, and.
³ Department of Pediatric Infectious Diseases.
⁴ Department of Pediatric Hematology/Oncology, Walter Reed National Military Medical Center, Bethesda, Maryland.

PMID: 26625395
DOI: 10.1093/jpids/pit038

Abstract

Nocardia species are ubiquitous soil-borne organisms that most commonly cause invasive disease in patients with defective cell-mediated immunity. We report a case of recurrent Nocardia sepsis in a patient with sickle cell disease and chronic iron overload, who was undergoing high-dose infusions of deferoxamine through a central venous catheter.

Keywords: Nocardia; hemoglobinopathies; iron chelation; sickle cell disease.

Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society 2013. This work is written by US Government employees and is in the public domain in the US.