Primary biliary cholangitis associated with warm autoimmune hemolytic anemia

J Dig Dis. 2016 Feb;17(2):128-31. doi: 10.1111/1751-2980.12303.

Abstract

There are many autoimmune diseases associated with primary biliary cholangitis (PBC), known as primary biliary cirrhosis; however, the association between PBC and warm autoimmune hemolytic anemia (wAIHA) has rarely been reported. It is documented that hemolysis is present in over 50% of the patients with chronic liver disease, regardless of the etiologies. Due to the clear and frequent relationship between PBC and many autoimmune diseases, it is reasonable to suppose that wAIHA may be another autoimmune disorder seen in association with PBC. Here we reported a 53-year-old female patient diagnosed with wAIHA associated with PBC.

Keywords: autoimmune hemolytic anemia; autoimmunity; cholestasis; primary biliary cirrhosis; ursodeoxycholic acid.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Hemolytic, Autoimmune / complications*
  • Anemia, Hemolytic, Autoimmune / drug therapy
  • Biopsy
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Liver / pathology
  • Liver Cirrhosis, Biliary / complications*
  • Liver Cirrhosis, Biliary / diagnosis
  • Liver Cirrhosis, Biliary / drug therapy
  • Liver Cirrhosis, Biliary / pathology
  • Middle Aged
  • Prednisolone / therapeutic use
  • Ursodeoxycholic Acid / therapeutic use

Substances

  • Glucocorticoids
  • Ursodeoxycholic Acid
  • Prednisolone