Posture effects on spontaneous limb movements, alternated stepping, and the leg extension response in neonatal rats

Physiol Behav. 2016 Mar 1:155:122-30. doi: 10.1016/j.physbeh.2015.12.001. Epub 2015 Dec 3.

Abstract

The development of postural control is considered an important factor for the expression of coordinated behavior such as locomotion. In the natural setting of the nest, newborn rat pups adapt their posture to perform behaviors of ecological relevance such as those related to suckling. The current study explores the role of posture in the expression of three behaviors in the newborn rat: spontaneous limb activity, locomotor-like stepping behavior, and the leg extension response (LER). One-day-old rat pups were tested in one of two postures--prone or supine--on each of these behavioral measures. Results showed that pups expressed more spontaneous activity while supine, more stepping while prone, and no differences in LER expression between the two postures. Together these findings show that posture affects the expression of newborn behavior patterns in different ways, and suggest that posture may act as a facilitator or a limiting factor in the expression of different behaviors during early development.

Keywords: Anogenital stimulation; Locomotion; Newborn; Posture; Quipazine; Rat.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • Forelimb / physiology*
  • Hindlimb / physiology*
  • Movement / drug effects
  • Movement / physiology*
  • Posture / physiology*
  • Quipazine / pharmacology
  • Rats, Sprague-Dawley
  • Serotonin Receptor Agonists / pharmacology

Substances

  • Serotonin Receptor Agonists
  • Quipazine