Abstract
We report a 3-year-old boy with anti-N-methyl-D-aspartate receptor encephalitis with a typical syndrome of movement disorder and encephalopathy and evidence of herpes simplex virus (HSV) type 1 infection on brain biopsy. HSV type 1 infection and anti-N-methyl-D-aspartate receptor encephalitis are temporally linked in some cases: this case suggests that prodromal HSV type-1 infection may be clinically subtle and easily missed.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-N-Methyl-D-Aspartate Receptor Encephalitis / complications*
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Anti-N-Methyl-D-Aspartate Receptor Encephalitis / diagnosis*
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Anti-N-Methyl-D-Aspartate Receptor Encephalitis / drug therapy
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Antiviral Agents / therapeutic use
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Autoantibodies
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Biopsy
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Brain / metabolism
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Brain / pathology*
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Brain / virology
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Child, Preschool
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Encephalitis, Herpes Simplex / complications*
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Encephalitis, Herpes Simplex / diagnosis*
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Encephalitis, Herpes Simplex / drug therapy
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Encephalitis, Herpes Simplex / virology
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Herpesvirus 1, Human / classification
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Herpesvirus 1, Human / genetics
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Humans
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Immunosuppressive Agents / therapeutic use
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Magnetic Resonance Imaging
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Male
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Polymerase Chain Reaction
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Treatment Outcome
Substances
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Antiviral Agents
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Autoantibodies
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Immunosuppressive Agents