Isolated cardiac lymphomas are very rare, especially in immunocompetent patients. As a consequence, little is known about the best therapeutic management and about patients' outcomes in these cases. Diffuse large B-cell lymphoma is the most frequent subtype; anthracycline-based chemotherapy has been the most successful treatment. We describe the case of a primary cardiac lymphoma in an immunocompetent 71-year-old man. As of December 2015, the patient had been in clinical remission for 2 years. The most relevant literature on primary cardiac lymphoma is reported and discussed.
Keywords: Biopsy, endomyocardial; cyclophosphamide; etoposide; heart neoplasms/therapy; immunocompetence; lymphoma, large B-cell, diffuse/diagnosis/drug therapy; lymphoma, non-Hodgkin/drug therapy; prednisone; rituximab; vincristine.