Detection of Virulence Genes and Growth Potential in Listeria monocytogenes Strains Isolated from Ricotta Salata Cheese

J Food Sci. 2016 Jan;81(1):M114-20. doi: 10.1111/1750-3841.13173. Epub 2015 Dec 14.

Abstract

Ricotta Salata is a traditional ripened and salted whey cheese made in Sardinia (Italy) from sheep's milk. This product is catalogued as ready-to-eat food (RTE) since it is not submitted to any further treatment before consumption. Thus, foodborne pathogens, such as Listeria monocytogenes, can represent a health risk for consumers. In September 2012, the FDA ordered the recall of several batches of Ricotta Salata imported from Italy linked to 22 cases of Listeriosis in the United States. This study was aimed at evaluating the presence and virulence properties of L. monocytogenes in 87 samples of Ricotta Salata produced in Sardinia. The ability of this product to support its growth under foreseen packing and storing conditions was also evaluated in 252 samples. Of the 87 samples 17.2% were positive for the presence of L. monocytogenes with an average concentration of 2.2 log10 cfu/g. All virulence-associated genes (prfA, rrn, hlyA, actA, inlA, inlB, iap, plcA, and plcB) were detected in only one isolated strain. The Ricotta Salata samples were artificially inoculated and growth potential (δ) was assessed over a period of 3 mo. The value of the growth potential was always >0.5 log10 cfu/g under foreseen packing and storing conditions. This study indicates that Ricotta Salata supports the L. monocytogenes growth to levels that may present a serious risk to public health, even while stored at refrigeration temperatures.

Keywords: Listeria monocytogenes; Ricotta Salata; challenge test; food safety; virulence genes.

MeSH terms

  • Animals
  • Bacterial Proteins / genetics*
  • Cheese / economics
  • Cheese / microbiology*
  • Humans
  • Italy
  • Listeria monocytogenes / genetics*
  • Listeria monocytogenes / growth & development
  • Listeria monocytogenes / isolation & purification
  • Listeriosis / microbiology*
  • Milk / economics
  • Milk / microbiology
  • Sheep
  • United States
  • Virulence Factors / genetics*

Substances

  • Bacterial Proteins
  • Virulence Factors